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Human GHR/Growth Hormone R (His Tag)
Description
Human GHR/Growth Hormone R (His Tag)GHR is the transmembrane receptor for growth hormone (GH) , belonging to the type I cytokine receptor family or Type 1 subfamily. It is expressed in various tissues, with higher expression in liver and skeletal muscle. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, inhibitor of cytokine signaling 1, and CISH. Specifications Synonyms GHR,GHBP,GH receptor; Uniprot No. P10912 1 Source Recombinant Human GHR Protein
phosphatidylserine (PS) is localized on the inner leaflet of the plasma membrane
Upon activation
the protein migrates to 35-40 kDa (FCGRT) & 13-14 kDa (B2M) based on Tris-Bis PAGE result
MELTDLLLA AMLLAVARL TLSSPVAPA CDPRLLNKL LRDSHLLHS RLSQCPDVD PLSIPVLLP AVDFSLGEW KTQTEQSKAQDILGAVSL LLEGVMAAR GQLEPSCLS SLLGQLSGQ VRLLLGALQ GLLGTQLPL QGRTTAHKD PNALFLSLQ QLLRGKVRF LLLVEGPTL CVRRTLPTT AVPSSTSQL LTLNKFPNR TSGLLETNF SVTARTAGP GLLSRLQGF RVKITPGQL NQTSRSPVQ ISGYLNRTHG PVNGTHGLFA GTSLQTLE ASDISPGAF NKGSLAFNLQGGLPPSPS LAPDGHTPF PPSPALPTT HGSPPQLHPLFPDPSTTM PNSTAPHPV TMYPHPRNL SQET
the KDR gene product (the murine homolog is the flk-1 gene product) and the flt4 gene product
during adult liver regeneration
(A) Accelerated Stability Test:
Several receptors in the TNF superfamily also contain intracellular death domains (DDs) that recruit caspase-interacting proteins to initiate apoptosis upon ligand binding
and Salmonella enterica 12%
The protease inhibitor tablet may discolor if left at room temperature for too long
FGF basic has also been shown to be crucial in modulating embryonic development and differentiation
Glypicans (GPC) are a family of heparan sulfate proteoglycans that are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor
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